TB-500 5mg lyophilised research peptide vial

TB-500 5mg

£18.99

  • ≥99% Purity (HPLC)
  • Batch-tested & CoA available
  • For research use only

TB-500 is the acetylated seven-residue actin-binding fragment of thymosin beta-4, supplied lyophilised for controlled in-vitro studies of cytoskeletal dynamics and cell migration.

This thymosin beta-4 fragment reproduces the LKKTETQ actin-binding domain rather than the full 43-amino-acid protein, giving a focused probe for actin modulation and matrix-interaction assays. For laboratory research only. Not for human use.

FOR LABORATORY RESEARCH USE ONLY

This product is supplied exclusively for scientific laboratory research. It is not intended for human or veterinary use or administration, therapeutic use, diagnostic use or clinical application.

Avanti Peptides does not provide advice regarding human administration, dosage, injection, reconstitution for administration, treatment protocols or therapeutic use.

Regulatory status

This product is sold as a laboratory research material and is not offered or promoted as a medicinal product. No therapeutic or medical claims are made for this product.

SKU: TB-500 Category:

Description

≥99% Purity (HPLC)
Batch-tested & CoA available
For research use only

About TB-500

TB-500 is the acetylated seven-residue actin-binding fragment of thymosin beta-4, supplied as a lyophilised research compound. It is worth being precise here: full-length Tβ4 is a 43-amino-acid protein, whereas this thymosin beta-4 fragment reproduces only the LKKTETQ actin-binding domain that carries most of the in-vitro activity.

Why researchers choose Avanti Peptides TB-500: Plenty of suppliers list TB-500 with full-length Tβ4 specifications — this page states the actual 7-residue fragment, and the material is released against those specifications.

Key features of TB-500

  • Peptide fragment (Thymosin Beta-4 actin-binding domain)
  • Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (7 amino acids)
  • Lyophilised solid — stable, easy to store, straightforward to reconstitute
  • Unit size: 5 mg / vial
  • Every batch released only after identity, purity, and appearance QC
  • Certificate of Analysis (CoA) and batch documentation available on request

TB-500 technical specifications

Product name TB-500
Synonyms Thymosin Beta-4 fragment; Tβ4(17-23); TB4 actin-binding domain fragment
Amino-acid sequence Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Class Peptide fragment (Thymosin Beta-4 actin-binding domain)
Molecular formula C31H52N6O11 (free base)
Molecular weight ~684.8 g/mol
CAS number 885340-08-9
Purity ≥99% (HPLC)
Physical form Lyophilised powder
Appearance White to off-white solid
Unit size 5 mg / vial
Note This is the 7-residue active fragment, not full-length 43-amino-acid thymosin beta-4

Reconstituting and storing TB-500

  1. Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
  2. Equilibrate: Allow vial and diluent to reach room temperature before opening.
  3. Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
  4. After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
  5. Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.

Looking for complementary materials? See Bacteriostatic Water 10ml — recommended diluent, BPC-157 5mg, GHK-Cu 50mg — complementary matrix-biology reagent.

TB-500 in research

Researchers use TB-500 to interrogate cytoskeletal organisation, cell migration and extracellular-matrix interaction readouts in model systems. Because the LKKTETQ motif is the region of Tβ4 that binds G-actin, this thymosin beta-4 fragment gives a focused probe of actin-sequestration biology without the confounds of the full-length protein.

Synthesis and quality assurance

Avanti Peptides manufactures TB-500 via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.

Frequently asked questions about TB-500

What is TB-500?
TB-500 is a 7-amino-acid peptide (sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln). It is used exclusively for in-vitro laboratory research. See the product overview above for full context.
How should I store the peptide?
Store lyophilised vials at 2–8 °C, away from light and moisture. After reconstitution, keep at 2–8 °C and use aliquots to minimise freeze–thaw cycles.
What diluent should I use for reconstitution?
Most laboratories use Bacteriostatic Water (10 ml). Always follow your lab’s standard operating procedures (SOPs) for the specific assay.
Do you provide batch documentation / Certificate of Analysis?
Yes. Batch documentation including test results (CoA) is available on request. If it is not attached to your order confirmation, contact our support team and we will add it immediately.
Is this product intended for human use?
No. This material is strictly for laboratory research only and is not intended for human consumption, clinical application, or veterinary use.

Legal & safety notice

For research use only. Avanti Peptides supplies this material strictly for laboratory research. This product is not a medication, food supplement, or cosmetic and is not intended for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will handle the material in accordance with your institution’s policies and all applicable laws and regulations.

External resources for researchers

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