MOTS-c 10mg lyophilised research peptide vial

MOTS-c — 10 mg

£19.99

  • ≥99% Purity (HPLC)
  • Batch-tested & CoA available
  • For research use only

MOTS-c is a mitochondria-encoded research peptide used in controlled in-vitro studies of cellular metabolism, stress-response signalling, and mitochondrial bioenergetics under non-clinical conditions.

This 16-amino-acid peptide originates from an open reading frame within the mitochondrial 12S rRNA region. Consequently, laboratories select it to explore pathways related to metabolic sensing, redox balance, and adaptive responses in model systems.
For laboratory research only. Not for human use.

FOR LABORATORY RESEARCH USE ONLY

This product is supplied exclusively for scientific laboratory research. It is not intended for human or veterinary use or administration, therapeutic use, diagnostic use or clinical application.

Avanti Peptides does not provide advice regarding human administration, dosage, injection, reconstitution for administration, treatment protocols or therapeutic use.

Regulatory status

This product is sold as a laboratory research material and is not offered or promoted as a medicinal product. No therapeutic or medical claims are made for this product.

SKU: MOTS-10MG Category: Tags: ,

Description

≥99% Purity (HPLC)
Batch-tested & CoA available
Lyophilised — stable at room temp
For research use only

Product overview

MOTS-c (Mitochondrial-derived peptide Open reading frame within 12S rRNA type-c) is a 16-amino-acid peptide encoded by the mitochondrial genome (12S rRNA). MOTS-c is a mitochondria-derived peptide (MDP) that has been studied in vitro for its roles in cellular metabolic regulation, AMPK pathway activation, glucose metabolism, and mitochondrial–nuclear communication. Avanti Peptides supplies MOTS-c as a lyophilised solid for stable, reproducible mitochondrial and metabolic biology research.

Why researchers choose Avanti MOTS-c: Mitochondrial-genome-encoded metabolic peptide for AMPK and energy-homeostasis studies — manufactured via validated SPPS and released only after identity, purity (≥99% HPLC), and appearance QC.

Key features

  • Mitochondria-derived peptide (MDP) for cellular metabolism and AMPK pathway research
  • Sequence: MRWQEMGYIFYPRKLR (16 amino acids, mitochondrial genome-encoded)
  • Lyophilised solid — stable, easy to store, and straightforward to reconstitute
  • Unit size: 10 mg per vial
  • Every batch released only after stringent identity, purity, and appearance QC
  • Certificate of Analysis (CoA) and batch documentation available on request

Technical specifications

Product name MOTS-c
Synonyms Mitochondrial-derived peptide c; 12S rRNA ORF peptide
Amino-acid sequence MRWQEMGYIFYPRKLR
Class Mitochondria-derived peptide (MDP, research use)
Molecular weight ~2174.6 g/mol
Purity ≥99% (HPLC)
Physical form Lyophilised powder
Appearance White to off-white solid
Unit size 10 mg / vial

Reconstitution & storage

  1. Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
  2. Equilibrate: Allow vial and diluent to reach room temperature before opening.
  3. Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
  4. After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
  5. Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.

Looking for complementary materials? See Bacteriostatic Water 10 ml and mitochondrial/metabolic research companions such as NAD+ and SS-31 (Elamipretide).

About MOTS-c in research

Researchers use MOTS-c to study mitochondria-to-nucleus retrograde signalling, AMPK-mediated metabolic regulation, glucose homeostasis, and the emerging biology of mitochondria-derived peptides. As a peptide directly encoded by the mitochondrial genome, MOTS-c provides a unique tool for investigating the role of mitochondrial peptidome in cellular energy regulation and metabolic disease pathways.

Synthesis & quality assurance

Avanti Peptides manufactures MOTS-c via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.

FAQs

What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondria-derived peptide (MDP) encoded by the 12S rRNA ORF of the mitochondrial genome (sequence: MRWQEMGYIFYPRKLR). It is used exclusively for in-vitro laboratory research into mitochondrial-nuclear communication, AMPK pathway activation, and cellular metabolism.
How should I store the peptide?
Store lyophilised vials at 2–8 °C, away from light and moisture. After reconstitution, keep at 2–8 °C and use aliquots to minimise freeze–thaw cycles.
What diluent should I use for reconstitution?
Most laboratories use Bacteriostatic Water (10 ml). Always follow your lab’s standard operating procedures (SOPs) for the specific assay.
Do you provide batch documentation / Certificate of Analysis?
Yes. Batch documentation including test results (CoA) is available on request. If it is not attached to your order confirmation, contact our support team and we will add it immediately.
Is this product intended for human use?
No. This material is strictly for laboratory research only and is not intended for human consumption, clinical application, or veterinary use.

Legal & safety notice

For research use only. Avanti Peptides supplies this material strictly for laboratory research. This product is not a medication, food supplement, or cosmetic and is not intended for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will handle the material in accordance with your institution’s policies and all applicable laws and regulations.

External resources for researchers

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