Description
About KPV
KPV is the C-terminal tripeptide fragment of α-melanocyte-stimulating hormone, supplied as a lyophilised research compound. This melanocortin tripeptide is used in cell-based and biochemical model systems to examine peptide-fragment pharmacology, receptor-adjacent signalling and structure-activity relationships alongside full-length melanocortin reagents.
Key features of KPV
- Melanocortin-derived tripeptide (3-amino-acid)
- Sequence: Lys-Pro-Val (3 amino acids)
- Lyophilised solid — stable, easy to store, straightforward to reconstitute
- Unit size: 10 mg / vial
- Every batch released only after identity, purity, and appearance QC
- Certificate of Analysis (CoA) and batch documentation available on request
KPV technical specifications
| Product name | KPV |
| Synonyms | Lys-Pro-Val; α-MSH(11-13) tripeptide fragment |
| Amino-acid sequence | Lys-Pro-Val |
| Class | Melanocortin-derived tripeptide (3-amino-acid) |
| Molecular formula | C₁₆H₃₀N₄O₄ (free base) |
| Molecular weight | ~342.4 g/mol |
| CAS number | 67727-97-3 |
| Purity | ≥99% (HPLC) |
| Physical form | Lyophilised powder |
| Appearance | White to off-white solid |
| Unit size | 10 mg / vial |
| Note | Counter-ion and hydration state may vary — refer to the vial label for lot-specific detail |
Reconstituting and storing KPV
- Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
- Equilibrate: Allow vial and diluent to reach room temperature before opening.
- Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
- After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
- Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.
Looking for complementary materials? See Bacteriostatic Water 10ml — recommended diluent, BPC-157 5mg, PT-141 10mg — full-length melanocortin comparator.
KPV in research
Researchers use KPV to explore how minimal peptide fragments behave in model systems, to assess signalling readouts that do not require the full α-MSH sequence, and to compare structure-activity relationships across the melanocortin family. Its very small size means this melanocortin tripeptide dissolves readily and diffuses quickly in culture, which suits short-timepoint assay designs.
Synthesis and quality assurance
Avanti Peptides manufactures KPV via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.




