MOTS-c 40mg lyophilised research peptide vial

MOTS-c 40mg

£59.99

  • ≥99% Purity (HPLC)
  • Batch-tested & CoA available
  • For research use only

MOTS-c is a 16-amino-acid mitochondrial-derived peptide supplied lyophilised for controlled in-vitro studies of cellular metabolism and mitochondrial bioenergetics.

Encoded within the mitochondrial 12S rRNA region, this research peptide is selected to explore metabolic sensing, redox balance and adaptive stress-response pathways in model systems. For laboratory research only. Not for human use.

FOR LABORATORY RESEARCH USE ONLY

This product is supplied exclusively for scientific laboratory research. It is not intended for human or veterinary use or administration, therapeutic use, diagnostic use or clinical application.

Avanti Peptides does not provide advice regarding human administration, dosage, injection, reconstitution for administration, treatment protocols or therapeutic use.

Regulatory status

This product is sold as a laboratory research material and is not offered or promoted as a medicinal product. No therapeutic or medical claims are made for this product.

Category:

Description

≥99% Purity (HPLC)
Batch-tested & CoA available
Lyophilised — stable at room temp
For research use only

About MOTS-c

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded by an open reading frame within the mitochondrial 12S rRNA gene, supplied as a lyophilised research compound. Because it originates from the mitochondrial rather than nuclear genome, this mitochondrial-derived peptide is a distinctive reagent for in-vitro work on metabolic sensing, redox balance and adaptive stress signalling.

Why researchers choose Avanti Peptides MOTS-c: Two methionines make this peptide oxidation-sensitive — it is lyophilised, sealed and released against identity and purity specifications to reach you unoxidised.

Key features of MOTS-c

  • Mitochondrial-derived peptide (16-amino-acid)
  • Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 amino acids)
  • Lyophilised solid — stable, easy to store, straightforward to reconstitute
  • Unit size: 40 mg / vial
  • Every batch released only after identity, purity, and appearance QC
  • Certificate of Analysis (CoA) and batch documentation available on request

MOTS-c technical specifications

Product name MOTS-c
Synonyms Mitochondrial ORF of the 12S rRNA type-c; mitochondrial-derived peptide
Amino-acid sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Class Mitochondrial-derived peptide (16-amino-acid)
Molecular formula C₁₀₁H₁₅₂N₂₈O₂₂S₂ (free base)
Molecular weight ~2,174.6 g/mol
CAS number 1627580-64-6
Purity ≥99% (HPLC)
Physical form Lyophilised powder
Appearance White to off-white solid
Unit size 40 mg / vial
Note Contains two methionine residues — protect from oxidation; store dry and dark

Reconstituting and storing MOTS-c

  1. Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
  2. Equilibrate: Allow vial and diluent to reach room temperature before opening.
  3. Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
  4. After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
  5. Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.

Looking for complementary materials? See Bacteriostatic Water 10ml — recommended diluent, SS-31 10mg — mitochondria-targeted comparator, NAD+ 500mg.

MOTS-c in research

Researchers use MOTS-c to probe metabolism-linked signalling and adaptive stress responses in cell systems, including AMPK-pathway readouts, redox-state markers and downstream transcriptional responses. As one of the first characterised mitochondrial-derived peptides, it is frequently the reference reagent when investigating mitochondrial-nuclear retrograde signalling in vitro.

Synthesis and quality assurance

Avanti Peptides manufactures MOTS-c via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.

Frequently asked questions about MOTS-c

What is MOTS-c?
MOTS-c is a 16-amino-acid peptide (sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg). It is used exclusively for in-vitro laboratory research. See the product overview above for full context.
How should I store the peptide?
Store lyophilised vials at 2–8 °C, away from light and moisture. After reconstitution, keep at 2–8 °C and use aliquots to minimise freeze–thaw cycles.
What diluent should I use for reconstitution?
Most laboratories use Bacteriostatic Water (10 ml). Always follow your lab’s standard operating procedures (SOPs) for the specific assay.
Do you provide batch documentation / Certificate of Analysis?
Yes. Batch documentation including test results (CoA) is available on request. If it is not attached to your order confirmation, contact our support team and we will add it immediately.
Is this product intended for human use?
No. This material is strictly for laboratory research only and is not intended for human consumption, clinical application, or veterinary use.

Legal & safety notice

For research use only. Avanti Peptides supplies this material strictly for laboratory research. This product is not a medication, food supplement, or cosmetic and is not intended for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will handle the material in accordance with your institution’s policies and all applicable laws and regulations.

External resources for researchers

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