SS-31 10mg lyophilised research peptide vial

SS-31 10mg

£26.99

  • ≥99% Purity (HPLC)
  • Batch-tested & CoA available
  • For research use only

SS-31 (elamipretide) is a mitochondria-targeted aromatic-cationic tetrapeptide supplied lyophilised for controlled in-vitro studies of cardiolipin interaction and bioenergetics.

This aromatic-cationic tetrapeptide associates with inner-mitochondrial-membrane lipids, supporting research into electron-transport organisation, redox balance and ATP-linked metabolism in model systems. For laboratory research only. Not for human use.

FOR LABORATORY RESEARCH USE ONLY

This product is supplied exclusively for scientific laboratory research. It is not intended for human or veterinary use or administration, therapeutic use, diagnostic use or clinical application.

Avanti Peptides does not provide advice regarding human administration, dosage, injection, reconstitution for administration, treatment protocols or therapeutic use.

Regulatory status

This product is sold as a laboratory research material and is not offered or promoted as a medicinal product. No therapeutic or medical claims are made for this product.

SKU: SS-31 Category:

Description

≥99% Purity (HPLC)
Batch-tested & CoA available
For research use only

About SS-31

SS-31 is a mitochondria-targeted tetrapeptide built on an alternating aromatic-cationic motif, supplied as a lyophilised research compound. That alternating charge pattern drives selective association with cardiolipin in the inner mitochondrial membrane, which is what makes this aromatic-cationic tetrapeptide a distinctive reagent for bioenergetics and redox research in vitro.

Why researchers choose Avanti Peptides SS-31: The non-proteinogenic Dmt residue is the hard part of this synthesis — identity and purity are confirmed on every SS-31 lot before release.

Key features of SS-31

  • Mitochondria-targeted aromatic-cationic tetrapeptide (4-amino-acid)
  • Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2′,6′-dimethyltyrosine) (4 amino acids)
  • Lyophilised solid — stable, easy to store, straightforward to reconstitute
  • Unit size: 10 mg / vial
  • Every batch released only after identity, purity, and appearance QC
  • Certificate of Analysis (CoA) and batch documentation available on request

SS-31 technical specifications

Product name SS-31
Synonyms Elamipretide; MTP-131; Bendavia; Szeto-Schiller peptide 31
Amino-acid sequence D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2′,6′-dimethyltyrosine)
Class Mitochondria-targeted aromatic-cationic tetrapeptide (4-amino-acid)
Molecular formula C₂₂₂H₄₉N₉O₅ (free base)
Molecular weight ~639.8 g/mol
CAS number 736992-21-5
Purity &g;99% (HPLC)
Physical form Lyophilised powder
Appearance White to off-white solid
Unit size 10 mg / vial
Note Contains non-proteinogenic Dmt residue; properties vary with counter-ion (acetate/TFA)

Reconstituting and storing SS-31

  1. Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
  2. Equilibrate: Allow vial and diluent to reach room temperature before opening.
  3. Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
  4. After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
  5. Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.

Looking for complementary materials? See Bacteriostatic Water 10ml — recommended diluent, MOTS-c 10mg — mitochondrial-derived comparator, NAD+ 500mg.

SS-31 in research

Researchers use SS-31 to examine interactions with cardiolipin-rich membrane domains, assess effects on respiratory-chain supercomplex organisation, and probe consequences for mitochondrial reactive-oxygen handling and ATP-linked metabolism. Because uptake is driven by membrane composition rather than potential, this aromatic-cationic tetrapeptide accumulates in mitochondria independently of membrane-potential collapse — useful in models where potential is already compromised.

Synthesis and quality assurance

Avanti Peptides manufactures SS-31 via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.

Frequently asked questions about SS-31

What is SS-31?
SS-31 is a 4-amino-acid peptide (sequence: D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2′,6′-dimethyltyrosine)). It is used exclusively for in-vitro laboratory research. See the product overview above for full context.
How should I store the peptide?
Store lyophilised vials at 2–8 °C, away from light and moisture. After reconstitution, keep at 2–8 °C and use aliquots to minimise freeze–thaw cycles.
What diluent should I use for reconstitution?
Most laboratories use Bacteriostatic Water (10 ml). Always follow your lab’s standard operating procedures (SOPs) for the specific assay.
Do you provide batch documentation / Certificate of Analysis?
Yes. Batch documentation including test results (CoA) is available on request. If it is not attached to your order confirmation, contact our support team and we will add it immediately.
Is this product intended for human use?
No. This material is strictly for laboratory research only and is not intended for human consumption, clinical application, or veterinary use.

Legal & safety notice

For research use only. Avanti Peptides supplies this material strictly for laboratory research. This product is not a medication, food supplement, or cosmetic and is not intended for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will handle the material in accordance with your institution’s policies and all applicable laws and regulations.

External resources for researchers

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