Description
About Ipamorelin
Ipamorelin is a selective ghrelin-receptor (GHSR-1a) agonist pentapeptide supplied as a lyophilised research compound. Built from non-proteinogenic residues including Aib and D-2-naphthylalanine, this secretagogue pentapeptide is valued in receptor pharmacology for its selectivity — it engages GHSR-1a without the off-target receptor activity seen with earlier secretagogues.
Key features of Ipamorelin
- Selective growth-hormone secretagogue pentapeptide (5-amino-acid)
- Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (5 amino acids)
- Lyophilised solid — stable, easy to store, straightforward to reconstitute
- Unit size: 5 mg / vial
- Every batch released only after identity, purity, and appearance QC
- Certificate of Analysis (CoA) and batch documentation available on request
Ipamorelin technical specifications
| Product name | Ipamorelin |
| Synonyms | NNC 26-0161; selective GHSR-1a agonist pentapeptide |
| Amino-acid sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Class | Selective growth-hormone secretagogue pentapeptide (5-amino-acid) |
| Molecular formula | C₃₈H₄₉N₉O₅ (free base) |
| Molecular weight | ~711.9 g/mol |
| CAS number | 170851-70-4 |
| Purity | ≥99% (HPLC) |
| Physical form | Lyophilised powder |
| Appearance | White to off-white solid |
| Unit size | 5 mg / vial |
| Note | Contains non-proteinogenic residues Aib and D-2-Nal; C-terminal amide |
Reconstituting and storing Ipamorelin
- Before reconstitution: Store lyophilised vials at 2–8 °C, protected from light and moisture.
- Equilibrate: Allow vial and diluent to reach room temperature before opening.
- Reconstitute: Add Bacteriostatic Water (10 ml recommended). Swirl gently — do not vortex.
- After reconstitution: Store at 2–8 °C. Prepare aliquots to minimise freeze–thaw cycles.
- Compatibility: Use only within protocols that comply with your institution’s SOPs and local regulations.
Looking for complementary materials? See Bacteriostatic Water 10ml — recommended diluent, CJC-1295 (No DAC) 5mg, GHRP-6 10mg — non-selective comparator ligand.
Ipamorelin in research
Researchers employ Ipamorelin to map GHSR-1a binding characteristics, profile cAMP/PKA and PLC/IP3/Ca²⁺ readouts, and compare potency and selectivity against less selective secretagogues in cell-based assays. That selectivity is the reason this secretagogue pentapeptide is often chosen as the clean control ligand when deconvoluting mixed receptor responses.
Synthesis and quality assurance
Avanti Peptides manufactures Ipamorelin via controlled, validated solid-phase peptide synthesis (SPPS) to deliver high purity and lot-to-lot consistency. Each batch undergoes identity verification, HPLC purity analysis (≥99%), and appearance inspection before release.




